Sierra Spr-32 Pro

With 32 detection spots available during each analysis cycle, several user-defined configurations are possible to maximize high-throughput SPR analysis. This can include 31 control-subtracted injections, up to 3 in-line controls or 4 targets per channel. The autosampler is compatible with a wide range of 96- and 384-well microtiter plates and the dual-plate sample deck with common rack position allows for increased automation.

When equipped with an optional plate handling robot, the instrument can function in high-throughput mode and can analyze more than 4400 samples per day, resulting in more than 13,200 control-subtracted interactions.

Sierra Spr-32 Pro可以轻松地通过API集成到自动调度软件中。

Sierra Spr-32 Pro系统是一种可健壮的仪器，旨在用于高通量应用，例如表位表征和抗体，片段或小分子筛选。

Simultaneous injection of up to eight samples facilitates high-throughput assay development and optimization, as well as rapid quantitative analysis of both crude and purified samples. Hydrodynamic isolation (HI) continuous flow microfluidic technology addresses samples as flowing streams onto the sensor array. This allows processing of 8 samples on a standalone system, which can be boosted to more than 4400 samples per day through optional plate handling robotics.

Sierra Spr-32 Pro系统的八个通道中的每个通道中的每个通道中的每个通道中配置了四个独立地寻址的检测点。可以在多达三个对照表面以及活性表面上同时测试样品。在许多SPR应用中，早期检测非特异性结合与对照蛋白的结合至关重要。

In small molecule screening and characterization, binding to serum proteins such as HSA and BSA is an integral part of drug development. The additional in-channel control halves the number of assay cycles required and improves data quality by eliminating potential variations between multiple sample preparations.

The SPR⁺detector combines imaging SPR (SPRi) with a high intensity laser light source and high-speed optical scanning. The result is improved signal-to-noise and improves accuracy when measuring small response changes.