Proven power
带有专利的SmartBeam激光器的小脚打印
Autoflex®MaxMaldi系统是通过我们熟练的技术创新建造的,旨在成为世界各地科学家,分析化学家和研究人员的强大工具。
以SmartBeam-II激光为特色,是Maldi仪器不可或缺的一部分
在自动旋转的核心®maX is our proprietary smartbeam-II solid state laser. With up to 2 kHz speed in MS mode and 200 Hz for MS/MS, time sensitive analysis – such as would be needed for biopharmaceutical integrity screening – can be made in minutes. The ionization efficiency of the smartbeam-II laser minimizes sample consumption and maximizes quality data output from each target position, even for complex samples. The ionization is gentle enough that tissue samples may be stained after analysis in MALDI MS Imaging workflows. Amenable to a variety of MALDI matrices, the smartbeam-II laser offers a long lifetime for a wide range of applications.
由直观软件驱动,实现无缝解决方案
Autoflex的价值和步行式接近性的关键组成部分®maX is the Compass software suite, including flexControl for data acquisition and flexAnalysis data analysis. Whether user driven or automated, these softwares support the generation of high quality data quickly and easily. Further, they work in combination with application specific software packages including BioPharma Compass®用于生物制药,聚合物的聚木和用于MALDI成像的SCILS™实验室。
维护变得容易
An analytical platform with this range of utility can become a workhorse in the lab, but ion source maintenance is made easy with the push button, IR-laser based self-cleaning of the Perpetual Ion Source. In less than 15 minutes, the autoflex®maX will be ready to resume its workload. Remote service capabilities with Bruker engineers support rapid troubleshooting as well as software and firmware updates on the spot.
从常规QC到发现和表征,Autoflex®maX MALDI-TOF and TOF/TOF systems offer versatility and reliability for the rapid analysis of challenging sample types.
像我们所有的Flex系列MALDI-TOF和TOF/TOF系统一样,AutoFlex®maX instruments are engineered to reliably provide high value data in daily operation. The application flexibility of autoflex®Max通过改进的动态范围增强,从而为各种质量范围内的分子物种提供了更完整的图像。
具有实验室友好的足迹,并可以选择从TOF升级到野外TOF/TOF功能,Autoflex®Max提供了真正的价值和分析多功能性,并延续了Bruker为每个实验室提供创新和可靠的解决方案的遗产。
Analysis of broad spectrum of molecules
All our MALDI-TOF mass spectrometers can analyze ions over a wide m/z range, enabling analysis of a broad spectrum of molecules, from smaller molecules, like lipids and peptides, up to polymers and intact proteins larger than 100 kDa. With our PAN panoramic focusing, peak resolution is maintained, and the new 10-bit digitizer of the autoflex®maX enhances dynamic range for a more complete view of sample components. In MALDI Imaging applications, this expansion of dynamic range can be invaluable for complex samples such as tissue, but is also beneficial for all applications, including QC workflows, direct TLC-MALDI, and polymer characterization.
Powerful solutions
The seamless integration of the high-quality data with our software suites SCiLS™ Lab, BioPharma Compass®, or PolyTools enable easy to use solutions for MALDI Imaging, protein characterization, industrial QC, polymer analysis, impurity evaluation, or characterization of additives.
使用自动旋转®maX, the application flexibility of MALDI-TOF MS is fully supported for rapid discovery and characterization workflows including
聚合物评价效率高和通知ation depth
MALDI-TOF mass spectrometry is a fast and easy method for polymer characterization, providing detailed information and mass accuracies far beyond traditional gel permeation chromatography. In many cases, oligomerically resolved polymer mass spectra may be obtained from the autoflex® maX, and from this data monomer units and end groups can be rapidly determined via our PolyTools software.
如果难以执行具有广泛质量分布的聚合物的质量计算(a> 1.2),则自动流动的动态范围增强®maX provides more data of potential value with the detection of lower intensity peaks and a broader polymer distribution.
快速生物制药产品特征
在生物制药的开发和生产中,快速,受过良好教育的决策可以减少早期开发到QC的应用的时间和成本。快速LC免费方法已经使用自动旋转开发®最大值以确定克隆选择的聚糖轮廓,在填充操作过程中执行快速ID测试以及各种传入商品的QC。
Antibody identification can be achieved rapidly using a dedicated 15-minute denaturation and digestion protocol, with the autoflex®最大化提供了丰富肽(肽质量指纹)的区分模式。与参考模式库相比,我们的Biopharma Compass中的专用评分算法®软件提供相似性得分和交通灯颜色编码,以简化正确的mAb序列匹配。可以使用PNGase F释放的聚糖从所有类型的抗体中快速制作克隆选择和QC屏幕。Biopharma指南针中产生的蝴蝶图®允许对不同MAB批次的聚糖池进行快速的视觉比较。
For Research Use Only. Not for use in clinical diagnostic procedures.