MPI PreClinical

临床前成像在健康状态和患病状态的生物学过程以及对药理，生理或环境挑战的反应中起着重要作用。最先进的分析技术的使用可以显着提高临床诊断和治疗常规。

布鲁克（Bruker）是最先进的临床前成像技术的著名提供商，从磁共振成像（MRI），计算机断层扫描（CT），正电子发射断层扫描（PET），单光子发射计算机断层扫描（SPECT）到其最小的最小成像技术，磁性粒子成像（MPI）。Bruker凭借将每项成像技术发展为最佳的每项成像技术，为科学家提供了新的方法和解决方案的创新，从而使地面制动发现。

Bruker constantly advances Magnetic Particle Imaging in the preclinical area, paving the translational way to clinical perspectives. The use of nanomaterials and their specific response to external magnetic fields is not only crucial for molecular imaging, but opens the door to the development of novel theranostic strategies, which in turn can improve patient outcomes and save lives.

Be inspired by the recent achievements of our outstanding MPI community in the life sciences and join us to take molecular imaging to the next level.

这是独家合作的结果，MPI系统结合了布鲁克在分析磁共振仪器和临床前磁共振成像（MRI）方面的领先专业知识，以及飞利浦在医学成像中的独特优势。

MPI是一种全新的临床前成像技术，具有巨大的潜力，可以提供新的策略，以了解器官，细胞和分子水平的疾病过程。借助新的MPI系统，Bruker进一步补充了其广泛的临床前成像产品组合，其中包括MRI，PET，SPECT和Micro-CT。

• Powerful 7-channel magnet design comprising drive, selection, and focus field technologies
  
• 最多46卷/秒
• ParaVision® acquisition and processing platform with DICOM export and import
• One-click data acquisition and reconstruction
• 完全灵活的序列设计
• 访问所有原始数据
• 推注注射通过Paravision®触发
• Wide-bore imager with 12 cm free access for imaging of mice, rats, guinea pigs and rabbits
• Bruker’s multi-modality animal handling system
• 1d Rx_只要coil inserts*
• Spatially selectivity via FFP
• 原位theranostic插入*
  
  _*optional
  

Three-dimensional images at millisecond intervals, providing the potential for real-time 3D imaging in vivo

MPI is a tomographic imaging technique that detects the magnetic properties of iron-oxide nanoparticles injected into the bloodstream to produce threedimensional images. The new technology, invented by Philips, and first introduced in a 2005 Nature paper, gave rise to a high aspirations for a new era in biological imaging.

Now Bruker has combined its expertise in technological innovation with its passion for pushing the boundaries of understanding, and launched the previously only envisioned possibilities to the imaging community.

比宠物快1,000倍
使用MPI，可以执行每秒46卷的成像，从而使生物过程以相等或更高的空间分辨率进行实时成像，而不是使用PET。

100％动物可视化
MPI measures the 3D distribution of injected iron oxide nanoparticles using a 25 kHz RF signal. This signal can easily be recorded from any depth within the animal allowing complete flexiblity in choosing areas of interest.

100% User-Friendly
Bruker的MPI系统结合了Paravision®6，并容纳Bruker的多模式床，从而使动物无缝过渡到Bruker MRI系统。

未想象的时间分辨率
在毫秒内获取高时间分辨率图像的能力允许在医疗和工业研究中进行新的应用，并最终在患者护理中进行时间分辨率是关键的。bob娱乐平台

Oncology

• Spatially selective tumor therapy
• in situ hyperthermia therapy (MFH)
• 温度监测
• 肿瘤疗法评估
• Cancer staging

神经病学

• fMPI, Neurodegeneration
• Acute stroke detection
• 局部和可逆的血脑屏障开口
• Direct brain cancer treatment
• 药物输送
• Localized MFH

Molecular Imaging

• 干细胞跟踪
• 细胞定量
• Cell viability
• Functionalized tracer
• Specific targeting
• Cell-labeling
• Inflammation

心血管

• Stenosis staging
• 斑块检测
• Plaque staging
• Real-time bolus tracking
• 速度重建
• 输出分数
• Functional parameter

治疗学

• 原位诊断和治疗系统
• Morphology
• Therapy planning and monitoring
• 空间选择性疗法
• Spatially selective hyperthermia (MFH)
• 基于图像的温度法

个性化医学

• 药代动力学
• 有针对性的药物输送
  
• Spatially selective drug activation

干预措施

• 设备致动/转向
• 空间选择性致动
• （纳米 - ）机器人转向

Lung Diagnosis

• Perfusion
• 通风