临床前磁粒子成像(MPI)扫描仪

MPI临床前

以毫秒的间隔三维图像,为体内实时3D成像提供了潜力
MPI

하이라이트

强调

革命
满足世界上第一个商业MPI系统,现在可以订购您自己的成像实验室
创新
Offering the largest range of preclinical imaging systems
MPIis a tomographic imaging technique that detects the magnetic properties of iron-oxide nanoparticles injected into the bloodstream to produce three-dimensional images.
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Magnetic Particle Imaging – one fascinating pillar of Bruker’s multimodal life science portfolio

Preclinical imaging plays an important role in the understanding of biological processes in both healthy and diseased states and of responses to pharmacological, physiological or environmental challenges. The use of state-of-the-art analytical technologies can significantly advance clinical diagnosis and therapy routines.

布鲁克is a renowned provider of state-of-the-art preclinical imaging technologies, ranging from Magnetic Resonance Imaging (MRI), Computed Tomography (CT), Positron Emission Tomography (PET), Single Photon Emission Computed Tomography (SPECT) to its youngest imaging technology, Magnetic Particle Imaging (MPI). With our mission to develop each imaging technology to its best, Bruker drives innovation in new methodologies and solutions for scientists enabling ground-braking discoveries.

布鲁克(Bruker)不断地在临床前区域进步磁性粒子成像,从而铺平了转化方式到临床观点。纳米材料的使用及其对外部磁场的bob综合游戏具体反应不仅对于分子成像至关重要,而且为新型疗法策略的发展打开了大门,这反过来又可以改善患者的结果并挽救生命。

受到我们杰出的MPI社区在生命科学领域的最新成就的启发,并加入我们,将分子成像提升到一个新的水平。

创新合作

独家合作的结果,MPIsystem combines Bruker’s leading expertise in analytical magnetic resonance instruments and preclinical Magnetic Resonance Imaging (MRI) with Philips’ unique strengths in medical imaging.

MPIis a completely new preclinical imaging technique with enormous potential to deliver new strategies to understand disease processes at the organ, cellular and molecular level. With the new MPI system, Bruker further complements its extensive preclinical imaging product portfolio that includes MRI, PET, SPECT and micro-CT.

특징

Features

  • 功能强大的7通道磁铁设计,包括驱动器,选择和焦点现场技术
  • Up to 46 volumes/sec
  • Paravision®获取和处理平台,带有DICOM出口和进口
  • 单击数据采集和重建
  • Fully flexible sequence design
  • Access to all raw data
  • Bolus injection triggering via ParaVision®
  • 宽孔成像仪,有12厘米的免费进入小鼠,大鼠,豚鼠和兔子的成像
  • 布鲁克的多模式动物处理系统
  • 1D Rxonly线圈插入*
  • 通过FFP在空间上选择性
  • In situ theranostic insert*

    *可选的

혜택

Benefits

以毫秒的间隔三维图像,为体内实时3D成像提供了潜力

MPI是一种层析成像技术,可检测注射到血液中的铁氧化物纳米颗粒的磁性特性,以产生三二二二二二二速率图像。这项由飞利浦发明的新技术首次在2005年的自然论文中引入,引起了人们对生物成像新时代的高度愿望。

现在,布鲁克(Bruker)将其技术创新方面的专业知识与对推动理解界限的热情相结合,并向成像社区推出了以前只有设想的可能性。

1,000 Times Faster Than PET
With MPI, imaging of up to 46 volumes per second can be performed, allowing real time imaging of biological processes at an equal or higher spatial resolution than with PET.

100% Animal Visualization
MPI使用25 kHz RF信号测量注射氧化铁纳米颗粒的3D分布。可以轻松地从动物内的任何深度记录该信号,从而使其在选择感兴趣的区域时完全柔韧性。

100%用户友好
布鲁克’s MPI System incorporates ParaVision® 6 and accommodates Bruker‘s multi-modal bed, providing a seamless transition of your animal to and from your Bruker MRI system.

Unimagined Temporal Resolution
The ability to acquire high time-resolution images in a matter of milliseconds allows for novel applications in medical and industrial research and ultimately patient care in which temporal resolution is key.

응용

Applications

Cardio-vascular 3D+t MPI bolus tracking (redscale) superimposed with a static 3D MRI dataset (grayscale) for morphological guidance. DOI: 10.1109/TMI.2020.3017160
MPI-based 3D+t flow velocity estimation represented as color-coded streamlines superimposed with MR-based morphological information. DOI: 10.1109/TMI.2020.3017160

肿瘤学

  • 空间选择性肿瘤疗法
  • 原位高温治疗(MFH)
  • Temperature monitoring
  • Tumor therapy assessment
  • 癌症分期

Neurology

  • FMPI,神经退行性
  • 急性中风检测
  • Local and reversible Blood Brain Barrier opening
  • 直接脑癌治疗
  • Drug delivery
  • 局部MFH

分子成像

  • Stem cell tracking
  • Cell quantification
  • 细胞活力
  • 功能化的示踪剂
  • 具体的目标
  • 细胞标记

Cardiovascular

  • 狭窄分期
  • Plaque detection
  • 牌匾舞台
  • 实时推注跟踪
  • Velocity reconstruction
  • Output fraction
  • 功能参数

Theranostics

  • 原位诊断和治疗系统
  • 形态学
  • 治疗计划和监测
  • Spatially selective therapy
  • 空间选择性高温(MFH)
  • Image-based thermometry

Personalized Medicine

  • Pharmacokinetics
  • Targeted drug delivery
  • 空间选择性药物激活

Interventions

  • Device actuation/steering
  • Spatially selective actuation
  • (Nano-)bot steering

肺诊断

  • 灌注
  • Ventilation

추천글

推荐

J. Schnorr博士,柏林Charité

“我们的小组正在氧化铁纳米颗粒领域工作,作为MPI,高温分子成像和血管造影的示踪剂。”

lübeck的T. Buzug教授(IMT(IMT)

“The possibility to collaborate closely with the development team of Bruker is a unique advantage."

Prof. T. Knopp, TUHH, Hamburg

„The Bruker MPI system allows us to develop new imaging sequences and to exploit the potential of MPI for medical applications."

Prof. T. Knopp, TUHH, Hamburg

“我将来对布鲁克的期望是第二代临床前MPI系统:更紧凑,但仍然非常灵活。”

추가정보

지원

Labscape

bob电竞官方网站服务和生命周期支持磁共振和临床前成像

布鲁克’s commitment to provide customers with unparalleled help throughout the buying cycle, from initial inquiry to evaluation, installation, and the lifetime of the instrument is now characterized by the LabScape service concept.

LabScape Maintenance Agreements, On-Site On-Demand and Enhance Your Lab are designed to offer a new approach to maintenance and service for the modern laboratory