Espetrymetria de Massa

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descubra novas formas de aplicar a spetration de massa aos desafiosanalíticosmais prementes da atualidade。
Espetrymetria de Massa

SoluçõesInovadorasde Espetrationde de Massa da Bruker

descubra novas formas de aplicar a spetration de massa aos desafiosanalíticosmais prementes da atualidade。inovaçõescomoa mobilidade dei在capturados(蒂姆斯),smartbeame lasers de varrimento para Formação de imagens MALDI-MS, que oferece uma verdadeira fidelidade de píxeis, assim como a tecnologia eXtreme Resolution (resolução extrema) FTMS (XR), capaz de revelar assinaturas da Estrutura Fina Isotópica (IFS), estão a levar a exploração científica para novos patamares. As nossas soluções de espetrometria de massa permitem aos cientistas fazer descobertas revolucionárias e obter conhecimentos mais aprofundados.

As linhas de produtos da Bruker incluem as seguintes tecnologias: timsTOF, MRMS, rapifleX MALDI-TOF/TOF, UHR-QTOF, Triplo Quadrupolo, HDX Solution, Toxtyper e TargetScreener HR. As nossas soluções de software líderes na indústria, tais como SCiLs Lab para Formação de imagens MS, MetaboScape e Biopharma Compass, são exemplos das nossas soluções que fazem o trabalho para si.

Tecnologias de Espetrometria de Massa

maldi-tof/tof

The analytical advantages of matrix assisted laser desorption ionization TOF MS have been demonstrated for more than 25 years. With inherent advantages including its speed (time to results) and application flexibility, the convenience and effectiveness of MALDI-TOF MS is magnified by virtue of its low sample volume requirements and broad sample content (salts, buffers) amenability. Dramatic increases in the depth of MALDI analyses have been made routine by intuitive software, and easy automation allows for high throughput solutions.

timsTOF

Trapped ion mobility spectrometry (TIMS) provides an additional dimension of separation, accelerating diverse research applications from 4D-Omics to MALDI Imaging. Powered by Parallel Accumulation Serial Fragmentation (PASEF®), Bruker’s timsTOF instruments offer next generation speed and sensitivity to identify and quantify challenging compounds.

MRMS

Bruker’s scimaX® and solariX series instruments are powered by MRMS (Magnetic Resonance Mass Spectrometry) technology. Compared with common FTMS technologies, these instruments feature unmatched eXtreme Resolution and mass accuracy. This enables routine Isotopic Fine Structure (IFS) analysis for a broad mass range, resulting in unmatched confidence for compound identification.

MS Software

每个巨大的质谱仪背后都有功能强大,有能力的软件。从生物制剂表征到质谱(MS)成像,我们的行业领先软件解决方案将MS数据转化为知识,并具有自动化和集成的工作流,赋予每个研究应用程序的能力。

MS解决方案

质谱法(MS)是一种令人难以置信的多样化和不断发展的技术,它在全球实验室中实施,以解决几乎所有分析问题。我们的高质量,直观的质谱仪增强了所有研发领域的能力,并在绩效中设定了新的标准。

QTOF

在从生物学和药物研究到临床毒理学等等的领域,四极飞机飞行时间(Q-TOF)MS彻底改变了我们如何识别和量化复杂混合物和未知化合物。我们的超高分辨率Q-TOF和LC-QTOF仪器处于这项技术的领先地位。

三倍的四边形

Due to its high sensitivity and specificity, triple quadrupole mass spectrometry (TQ MS) is a major tool in the fields of food testing, drug metabolism, pharmacokinetics, forensic toxicology, environmental studies, and biological analyses. Bruker’s unique elliptical ion path delivers new levels of performance for LC- and GC-TQ MS.

Ion Trap

Bruker leads the industry in ion trap technology, offering a comprehensive series of systems that enable structural confirmation and screening applications in routine labs, drug quantification and metabolite identification, and post-translational modification (PTM) characterization using electron transfer dissociation (ETD) technology.

LC-MS

当耦合到质谱(MS)系统时,液相色谱(LC)分析的值和多功能性会显着放大。我们通过强大的,灵活的仪器和功能强大的供应商 - 敏捷的软件来访问广泛的高性能液相色谱(HPLC)解决方案。

Áreas de Aplicação da Espetrometria de Massa

蛋白质组学

Fully addressing the complexity of the proteome can only be achieved using orthogonal approaches. Bruker offers a dedicated panel of solutions to deal with these challenges. The timsTOF Pro powered by PASEF® enables for the first time fast, ultra-sensitive shotgun proteomics and relative protein quantitation at high throughput over large cohort and low abundance sample studies, at an unprecedented level of robustness.

MALDI Imaging

MALDI成像的应用区域多样性和增长,这是由于该技术的无标签性质以及通过分子量区分化合物的能力。Bruker提供了MALDI成像系统,这些成像系统结合了新型MALDI技术,以完成任何有针对性或未定位的成像研究。TimStof Flex添加了高空间分辨率MALDI成像源,专门设计用于解决分子分布并将空间维度带入OMICS分析。

Metabolomics

TimStof Pro上的新型4D工作流正在革新下一代代谢组学,并为每个已知和未知化合物测量的其他大规模和准确的CCS信息提供了其他大规模和准确的CCS信息。

Pharma and BioPharma

从加速早期发现的速度,增加了信心,因为候选人从药物开发转移到临床试验,通过配方并确保良好的质量保证和生产控制。在每个阶段,成功都取决于使用正确的技术,生成最佳数据,并获得最深的见解。

食物

As today’s highly globalized supply chains are very vulnerable, food safety and food protection are matters of intense environmental, public and economic concerns. Advanced analytical methods and techniques for food control can help to safeguard human health and even lives.

Polymer Analysis

MALDI-TOF technology offers a unique depth of characterization for many diverse polymer classes. Including bulk material screens, pharmaceutical development, or finished surface analyses, MALDI-TOF MS offers direct molecular weight distributions in fast and versatile workflows.

仅用于研究。不用于临床诊断程序。