SkyScan 2214

3D X-ray Microscopy at the Nanoscale

命令的最终表现

HerostagesKyscan2214

Highlights

Highlights

300 x 400毫米
largest size that can be accommodated
无论样品是巨大的还是很小的,Skyscan 2214具有灵活性来对它们进行成像。
160凯夫
penetrating power
快速更换灯丝以最高渗透或实验室的W之间切换以最高分辨率
<500 nm
真3D空间分辨率
There are many ways to define resolution, but the most important is the ability to resolve 2 features in the resulting 3D model.

Skyscan 2214 - 纳米级X射线显微镜

新的多尺度X射线纳米仪Skyscan 2214涵盖了单个仪器中最宽的物体大小和空间分辨率。它为所有类型的生物样品(包括矿化组织,软组织,植物,昆虫,古生物学样本等)提供了独特的3D成像和精确建模的可能性。

该仪器允许对物体的内部微观结构进行扫描和3D非破坏性重建,直径至300mm,以及用于小样品的亚微米分辨率。

该系统包含一个“开放式”传输X射线源,其斑点尺寸<0.5微米和钻石窗口。它可以配备多达四个不同的X射线探测器,以实现最大的柔韧性:大型物体的平板,11MP冷却的CCD,具有广阔视野,11MP冷却的CCD具有中等视野,以及8MP冷却的CCD,用于最高空间分辨率。自动可变采集几何形状和相对比增强功能可以在相对短的扫描时间中获得最佳质量。

Skyscan 2214由3D.Suite补充。这个全面的软件套件涵盖了GPU加速重建,2D/ 3D形态分析以及表面和音量渲染可视化

SKYSCAN 2214 walk-up video

什么是XRM?视频

特征

Key Features

Skyscan 2214功能

Source

The SKYSCAN 2214 uses a latest generation open-type X-ray source. The source offers true spatial resolution below 500 nm, an X-ray energy up to 160 keV and source power up to 16 W. The source is practically maintenance-free with an extremely easy pre-aligned filament replacement procedure.

Skyscan 2214具有带有钻石窗口的开放型(泵送)纳米焦X射线源。它产生的X射线束从20 kV到160 keV,并提供两种类型的阴极。钨(W)阴极在最高160 kV的整个加速电压下运行,并提供一个斑点尺寸降至800 nm。甲状腺六角杆(LAB6)阴极可用于将电压从20 kV加速至100 kV,并提供小于500 nm的X射线束的斑点,以实现成像和3D重建方面的最高分辨率。JIMA分辨率模式表明500 nm结构可以轻松解析。

为了使焦点斑点大小和发射点位置的长期稳定性,X射线源配备了液体冷却系统,该系统包含重新循环器,可提供冷却液的精确温度稳定性。

Skyscan 2214功能

探测器

The SKYSCAN 2214 can be equipped with up to four X-ray cameras for ultimate flexibility: three CCD cameras with different resolution and field of view and one large-area flat panel detector. All cameras can be selected with a single mouse click. The different CCD cameras can be retro-fitted at any point of time during the system’s lifetime.

所有三个CCD都可以在中央梁位置和两个偏移位置拍摄图像,以使视场的视野增加一倍。两个偏移位置中的图像将自动缝合,并补偿偏移和可能的强度差异。

使用具有小像素尺寸的CCD检测器可以将高分辨率成像和3D重建的扩展为大对象。内置检测器的灵活性可以根据对象大小和密度调整视野和空间分辨率。来自兴趣量的高级重建提供了对大分子的选定部分具有高分辨率的扫描,而不会损害图像质量。

Additionally, the field of view can be increased horizontally and vertically by using offset camera positions and vertical object movement.

Skyscan 2214功能

原位阶段

The high-precision object stage of the SKYSCAN 2214 supports objects up to 300 mm diameter and 20 kg in weight. The air-bearing rotation motor allows precise rotation of objects at very high accuracy, and the integrated micro-positioning stage guarantees a perfect sample alignment.
The SKYSCAN 2214 has a large and easily accessible sample chamber to allow scanning of big objects as well as mounting of optional stages. On top plenty of space is available for peripheral equipment.

Bruker材料测试阶段旨在执行高达4400 N的压缩实验和最高440 N的拉伸实验。所有阶段都可以通过系统的旋转阶段自动通信,而无需任何电缆连接。使用提供的软件,可以设置计划的扫描实验。

布鲁克's heating & cooling stages can reach temperatures of up to +80 °C or 30 °C below ambient temperature. Just like the other stages, no extra connections are needed, and there is an automatic recognition of the stage. Using the heating & cooling stages, samples can be examined under non-ambient conditions, to evaluate the effect of temperature on the sample’s microstructure.

Skyscan 2214与Deben的阶段完全兼容。使用随附的适配器,可以简单地将Deben阶段放在Skyscan 2214的旋转阶段。

Cooling Stage
Material Testing Stage
Deben舞台

申请

Highlighted Applications

矿化组织

Skyscan 2214提供了最终的NanoCT成像性能,而无需妥协。安装了四个摄像机 - 一种大格式6百万像素CMOS平板面板,用于成像高电压和大骨骼或牙齿样品,以及三个小格式检测器,用于每个想象的骨骼的最佳选择和X射线能量窗口的最佳选择样品扫描。

Submicron voxel scans provide crystal clear resolution of bone osteocyte lacunae and micro-scale mineralization structure, as well as architecture of biomaterial scaffolds at nano-scale resolution.

相位检索(Paganin)提供了对迄今为止研究的骨微矿化模式分析的新维度。

Orthopedic research with sheep, primate or similar models is handled with the 14cm scan field of view and 160kV x-ray source. Realize your orthopedic and biomechanical research goals with mechanical testing and temperature control stages.

Morphometry with comprehensive 3D and 2D parameters, with densitometry including BMD calibration references over the preclinical size range. Advanced 3D image analysis functions include 3D registration, adaptive thresholding, Euler connectivity, fractal, anisotropy and stereology, filtering, Boolean logical operators and much more.

软组织

Ex vivo nano-CT scanning of biological tissues, with sub-micron pixel size, is like histology or electron microscopy but in true, deep 3D - a fantastic method to show internal structures non-destructively. Contrast agents or chemical drying can improve the image quality by further enhancing or differentiating tissue densities. The SKYSCAN 2214 is playing a leading role in the emergence of a new imaging discipline – microCT histology and histomorphometry.

The unmatched versatility of this system ensures that each sample will be scanned with optimized parameters and the best resolution and contrast.

Four cameras are fitted – a large format 6 megapixel flat panel for imaging up to high voltages and large tissue samples, and a range of three small format cameras for the optimal choice of resolution and x-ray energy window for every conceivable sample scan.

全面的3D图像分析能力,包括形态计和光密度计,3D注册,分割和高级图像处理方法。

Plant and Animal Biology

MicroCT非常适合可视化内部生物结构的最细节。这种成像方法创建了纳米尺度的3D X射线衰减图,而不会损害或破坏扫描的物体。实际上,所有生物组织几乎可以通过几乎不需要特殊样品处理来可视化和分析。亚微米素分辨率允许对小昆虫和植物或种子结构进行成像,并具有强大的放大倍率和丰富的细节。

扫描室中的空间以及旋转阶段的精度确保可以扫描所有类型的样品,从小斑马鱼和保存的动物学和植物样品到盆栽的植物和岩石填充的化石。

Four cameras are fitted – a large format 6 megapixel flat panel for imaging up to high voltages and large samples, and a range of three small format cameras for the optimal choice of resolution and x-ray energy window for every conceivable biological sample scan.

该软件套件可以通过全面的3D和2D参数实现形态计量学,高级3D图像分析功能包括3D注册,自适应阈值,Euler连接,分形,各向异性和立体,过滤,Boolean逻辑运算符等。

规格s

Skyscan 2214规格

Feature

规格

益处

X-ray source

20-160 kV

16 W max.

User exchangeable filament

优化最大功率(W)或最大分辨率(LAB6)

Rotatable diamond window for maximum lifetime

X-ray detector

6 MP活动像素平板板

11Mp large format cooled CCD

11Mp mid format cooled CCD

8 MP HI-RES冷却CCD

多种像素和检测器的大小可以在检测器分辨率,覆盖范围和计数统计数据之间平衡

可提供1、2、3或4个检测器

Field upgradable to add detectors

图像格式

Up to 8000 x 8000 x 2300 pixels after a single scan

User selectable image size allows balance of dataset size and needed resolution

数据收集后软件允许裁员

决议

60 nm最小的像素大小
<500 nmlow-contrast resolution (10% MTF)

Simple graphics control for optimizing experiment resolution based on selected detector, sample and detector distance

Adjustable source focus size to balance maximum power and resolution

定位准确性

<50 nm for rotation
Anti-vibration granite platform with pneumatic leveling

空气轴承样品阶段提供平稳的旋转

Simple chuck style mounting of sample posts

高级材料研究阶段的机械和电界面bob综合游戏

Maximum Object Size

直径为300毫米(140毫米扫描尺寸)

400毫米长

最大物体重量20公斤

Both the power and room to scan large samples

靠近源的小样品的精确定位以最大化放大倍率

Dimensions W 1800毫米X D 950毫米X H 1680毫米

重量:1500公斤

Efficiently designed to optimize use of lab space

源维护交流cess via interlocked large sliding door

软件

位置,扫描,重建和分析

Bruker XRM解决方案包括收集和分析数据所需的所有软件。具有用户指导参数优化的直观图形用户界面支持专家和新手用户。通过使用最新的GPU动力算法,重建时间大大减少。CTVOX,CTAN和CTVOL结合在一起,形成了一个强大的软件套件,用于模型的定性和定量分析。

Measurement Software:
SKYSCAN 1272 – Instrument control, measurement planning and collection

重建软件:
NRECON – Transforms the 2D projection images into 3D volumes

Analysis Software:
DATAVIEWER– Slice-by-slice inspection of 3D volumes and 2D/3D image registration

CTVOX– Realistic visualization by volume rendering

CTAN– 2D/3D image analysis & processing

ctvol- 可视化表面模型以导出CAD或3D打印

News & Events

支持

SKYSCAN 2214 - Service & Support

可用服务包括bob电竞官方网站

  • Help desk support from highly-skilled troubleshooting professionals, to isolate and resolve hard- and software problems
  • 基于Web的远程仪器服务用于服务诊断和应用程序支持bob电竞官方网站
  • 与帮助闪电合并的现实支持 - 您身边的虚拟工程师(视频)
  • Planned maintenance, according to your requirement
  • 客户现场维修和维护服务bob电竞官方网站
  • 备件的可用性通常在全球的几个工作日或几个工作日之内
  • 安装资格,运营资格 /bob电竞官方网站绩效验证的合规服务
  • 现场计划和搬迁

布鲁克支持

在我们的支持网站you will find:

软件更新

  • 系统软件更新可在线提供给注册用户。

Documentation

  • 产品手册和安装指南可在线提供给注册用户。

实验室

bob电竞官方网站服务和生命周期支持磁共振和临床前成像

布鲁克致力于在整个购买周期内为客户提供无与伦比的帮助,从初始查询到评估,安装和仪器的寿命,现在以LabScape服务概念为特征。bob电竞官方网站

LabScape Maintenance Agreements, On-Site On-Demand and Enhance Your Lab are designed to offer a new approach to maintenance and service for the modern laboratory