MS软件

SCiLS™ Lab

The world-leading software for analysis of mass spectrometry imaging data from all major mass spectrometry vendors, including Bruker’s FLEX series and MRMS

Turn data into knowledge

Analysis and visualization in one software

scils

Highlights

MS软件

SCiLS™ Lab

便于使用
支持来自其他主要质谱供应商的所有主要Bruker仪器和数据。
Visualization
2D and 3D visualization allows a multitude of applications in pharmaceutical, medical, and industrial research.
Analysis
下一代机器学习算法的高级处理和分析。
Integrated
MALDI分子药物成像仪的整体部分,Rapiflex Maldi Tissuetyper和TimStof Flex的空间工作流程。

Eigenschaften

SCiLS Lab

Software for MS imaging data analysis

对于Bruker的软件,MALDI成像数据的分析和可视化从未如此简单。

Powerful visualization and reporting

  • Instant and intuitive visualization of ion images and mass spectra
  • 可视化空间复合分布和分布模式的灵活渲染选项
  • 引人入胜的统计图和报告
  • Volumetric visualization of 3D MS imaging studies (optional)


Advanced data processing and analysis

  • Advanced machine learning algorithms for data sets of virtually unlimited size
  • Comparative analysis for uncovering discriminative and correlated spectral features
  • Unsupervised spatial segmentation and component analysis for untargeted clustering and data mining
  • Metadata annotations for characterizing regions in clinical and pre-clinical studies
  • 用于分类未标记样品的分类模型
  • 基于稀释系列的分析物定量


工作流程和可扩展性

  • 用于各种目标和无靶向的空间工作流程的综合工具
  • 与数字病理学的组织学注释的整合
  • 用于自动报告和高级工作流集成的广泛应用程序编程接口(API)
  • 将MS成像数据导出到开放行业标准IMZML
  • 从IMZML或各种第三方供应商的成像数据格式导入MS成像数据集(可选)
SCILS™实验室是该行业的首选工具,可从质谱成像数据中获取新的见解。该软件在科学和行业中使用,在分析和可视化中设定了新的标准,简化了日常工作并增强了研究成果。


系统要求
建议以下系统要求:

  • Intel Core i7处理器或Intel Xeon处理器(或等效)至少4个内核
  • Microsoft Windows 10 64 Bit operating system
  • 64 GB of RAM
  • 1 TB固态驱动器(SSD,SATA III或M.2)
  • Full HD display (1920 x 1080)
  • 支持OpenGL 3.2的图形板


为了获得最佳性能,应使用SSD托管SCILS™实验室数据文件。使用多个SATA III或M.2 SSD的RAID0配置实现最佳系统性能。

涡流

SCiLS Lab

用于分析质谱成像数据的世界领先软件

SCILS™实验室集成了来自所有主要质谱供应商的数据,包括Bruker的FLEX seriesMRMS, as well as datasets provided in the open imzML format. FortimsTOF fleX离子迁移率数据,SCILS™实验室显示允许CCS感知数据解释的质量移动离子图像。

Comparative analysis of multiple samples can be visualized in both 2D and 3D, enabling a multitude of applications inpharmaceutical drug development,组织分辨的生物标志物发现, and translational pathology research to complement immunohistochemistry.

SCiLS™ Lab supports intuitive workflows for MSI quantitation of target molecules directly from tissue. It integrates with the SpatialOMx workflow from代谢®并想象着检测到的特征(代谢物,脂质,聚糖)的注释的MALDI分子组织图像。为了与组织学集成,SCILS™实验室为功能强大的开源软件提供了一个接口QuPath广泛用于数字病理学。

安温登根

SCiLS Lab

所有类别分子的无标签MS成像 - 从蛋白质到小分子

SCILS™实验室可用于分析多个谱技术成像数据集, allowing them to be loaded and arranged side by side. Compositions of data sets of virtually unlimited size can be visualized and statistically analyzed for detailed interpretation. Moreover, SCiLS™ Lab can be used to generate and visualize 3D models from consecutive 2D MALDI imaging datasets.

Distribution of three distinct m/z values in a 3D reconstruction of 49 sagittal mouse brain sections containing a non-metastasizing cerebellar tumor with SCiLS™ Lab.
Statistical analysis with SCiLS™ Lab: Automatically group samples according to meta-data provided with experiments – perform classification and prediction with machine learning methods for tissue typing or biomarker discovery.


临床研究中的大型样本队列
在临床生物标志物研究中discovery of discriminating ions,需要分析大量样本队列和大量数据。SCILS™实验室使将样本元信息链接到MALDI MSI数据,节省时间并避免错误。使用数字病理学的组织学注释使用功能强大且广泛使用的开源应用程序进行集成QuPath.

Automatic elucidation of spectral features discriminating pathophysiological alterations are easily performed. With just one click, SCiLS™ Lab automatically quantifies how well ions discriminate between different biological states. The resulting list of novel biomarker candidates can be easily exported for subsequent analysis.

Discover the powerful data mining capabilities that are now just a single click away!

Whole body imaging
可视化药物和代谢物分布关于样本处理,获取和计算数据分析,全身组织中的部分仍然是一种具有挑战性的方法。

SCILS™实验室为整个MALDI MSI数据分析工作流提供工具。可以使用一个软件来处理由数百万个光谱组成的多个数据集,从多个单个数据集对光谱预处理的注册到综合统计分析。

Label-free targeted imaging and distribution mapping for drug discovery and DMPK/PD: Low operational cost and high specificity – differentiate drug and metabolite distributions, quantify target compounds, and integrate with histology.

Webinare

Meinungen

"With SCiLS Lab our team saved endless hours of manual comparisons. This unique feature was eagerly anticipated by us."

Rita Casadonte, PhD, Proteopath GmbH