Skyscan 1278

The SKYSCAN 1278 is a high throughput, stand-alone, desktop in vivo micro-CT for scanning small laboratory animals (mice, rats, ...).

The large image field of view (up to 80 mm wide and 200 mm long) allows full body mouse scanning with a single camera field of view. Variable X-Ray energy combined with a range of filters ensures optimal image quality for diverse research applications including pneumology, cardiology and body composition analysis. The system can perform scanning with continuous gantry rotation and in step-and-shoot mode with scanning cycles down to 7.2 sec.

Furthermore, the SKYSCAN 1278 in vivo micro-CT administers a low radiation dose to the animals allowing multiple scans in longitudinal preclinical studies without the risk of unwanted radiation - induced side effects. The fully integrated physiological monitoring package allows monitoring and controlling the animal's wellbeing at all times through a video stream, ECG, temperature and breathing detection.

Skyscan 1276由3D.Suite补充。这个广泛的软件套件涵盖了GPU加速重建，2D/ 3D形态学分析以及表面和体积渲染可视化。

The user interface of the SkyScan1278 system is simple and intuitive. The instrument can be controlled from the computer screen and also from the embedded force-sensitive touchscreen, which can be operated by gloved hands. The touchscreen allows selection of scanning protocol, adjusting animal bed position and control of imaging and scanning. Where multiple animal scans are started from the touchscreen, the software will automatically save acquired data to separate subfolders with incrementally assigned folder names and dataset file prefixes.

生理监测系统包括对动物进行实时运动检测，心电图和呼吸检测以及温度稳定的视频监测。一个5百万像素的颜色摄像头安装在动物床上方以及白色LED照明上，以在扫描过程中引入动物的实时图像。该软件从图像的用户选择区域分析了视频流，其中可见呼吸运动。这些运动被转换为运动波形，为时间分辨的重建提供呼吸时间标记。动物床上的面膜连接到空气/气流传感器以直接呼吸检测。动物盒中的ECG电极连接到敏感的ECG放大器。呼吸和心电图信号都在屏幕上进行数字化并显示为实时轮廓。监测还包括加热气流的温度稳定，该气流将扫描动物保持在选定的温度下，以防止在麻醉下冷却动物。

Calculating and visualizing body composition of the mouse or rat is easily accomplished in just a few steps. No additional contrast agent is needed to analyze body fat as it is one of the naturally occurring x-ray densities in the body, the others being lean tissue, lung tissue and bone. With the SKYSCAN 1278 body tissue composition analysis can be highly automated and high-throughput, suitable for genetic screening.

• Fastest scan of only 7.2 seconds and streamlined operation makes high throughput of mice or rats easy to obtain. Optimized filters and voltages ensure the least possible radiation dose.
• 生理监测是摩西班的设计中心in vivo扫描仪，不是附加组件。高质量的视频，视频移动和压力通过呼吸监测，ECG和恒温器控制的变暖，并带有用于外部生理仪器的端口。
• Advanced animal cassettes connected for full physiological monitoring and anesthesia provision yet detachable with a single locking button – the universal Brukerin vivobed.
• Full in-house software solution for tissue segmentation and 3D analysis, 3D registration of sequential scans to map progression with growth and time.

Skyscan 1278是用于小鼠和大鼠的多功能心脏成像解决方案。借助大型且快速的CMOS平板X射线相机，将老鼠的心脏和肺部成像。扫描仪和随附的软件在短扫描时间内提供了急剧时期的心脏，肺和双（心脏肺门控）图像，并具有安全的电离辐射水平。与所有体内扫描仪一样，生理监测是仪器的核心，动物的福利是最重要的。

• High quality video, breathing monitoring by video-movement and pressure, ECG and thermostat-controlled warming. External access to the scan chamber for ducts including capillary tubes (continuous injection).
• 高级动物盒连接，以进行完整的生理监测和麻醉，但可以使用单个锁定按钮 - 通用的Bruker体内床。大鼠的大碳纤维床。支持第三方设备，例如呼吸机（例如Scireq FlexiventTM）。
• 全面的时间门控解决方案：前瞻性和回顾性，基于时间和图像的内在门控。连续旋转可用于快速低剂量门控扫描。
• Full in-house software solution for cardiac function analysis in 4D: ejection volume, other cardiac chambers and aorta, time-analysis of cardiac wave-train including regularity and fractality, with flexible segmentation and analysis of the cardiac cycle in CT-Analyser software.

Bruker XRM solutions include all software needed to collect and analyze data. An intuitive graphical user interface with user guided parameter optimization support both expert and novice users. By using the latest GPU powered algorithms, reconstruction time is substantially reduced. CTVOX, CTAN and CTVOL combine to form a powerful suite of software for both qualitative and quantitative analysis of models.

测量软件：
Skyscan 1272 - 仪器控制，测量计划和收集

Reconstruction Software:
NRECON – Transforms the 2D projection images into 3D volumes

Analysis Software:
DATAVIEWER- 逐片检查3D卷和2D/3D图像注册

CTVOX– Realistic visualization by volume rendering

CTAN- 2D/3D图像分析与处理

ctvol– Visualization of surface models to export for CAD or 3D printing