First 1.2 GHz NMR System Delivered to CERM at the University of Florence, Italy
BALTIMORE--(BUSINESS WIRE)-- At the Experimental Nuclear Magnetic Resonance Conference 2020 (ENC),Bruker Corporation(Nasdaq: BRKR) announces the recent delivery of the world’s firstAvance™ NEO1.2 GHzNMR system to the CERM at the University of Florence, Italy, and the first installation of anAvance NEO1.1 GHzsystem at St. Jude Children’s Research Hospital in Memphis, TN. Bruker has now successfully brought three 1.2 GHz magnets to field at its Swiss GHz-class magnet facility. Moreover, Bruker has received two additional 1.2 GHz customer orders in late 2019, with first orders from the United States (The Ohio State University) and Korea (KBSI).
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Bruker 1.2 GHz NMR Spectrometer at CERM at University of Florence, Italy (Photo: Business Wire)
Professors Lucia Banci and Claudio Luchinat at the CERM of University of Florence, stated: “We are very excited to have received the world’s first 1.2 GHz NMR spectrometer in our lab, a result of multiple years of research and development at Bruker in various fields ranging from superconducting material science, magnet design, probe technology and NMR spectrometer electronics. We are looking forward to putting the instrument to use in our research on the structures and function of proteins linked to neurodegenerative diseases, such as Alzheimer’s and Parkinson’s Diseases, as well as in cancer research.”
新的GHz-class NMR technologyis now enabling novel research infunctionalstructural biology of proteins and protein complexes. Research includes the structures, dynamics and function of important globular proteins, membrane proteins and protein complexes. Ultra-high field NMR is also unique in that it can study the properties and interactions of intrinsically disordered proteins (IDPs), which make up 30-50% of the human proteome. IDPs play a crucial functional rule in fundamental cell biology, and they are also implicated in many instances of disease biology.
Dr. Falko Busse, Bruker BioSpin's Group President, stated: “We have continued to make good progress with our novel GHz-class NMR magnet technology, and we now focus on the installation of the world’s first 1.2 GHz NMR spectrometer in Florence, and on ramping up the small series production of additional 1.2 GHz systems. We have so far brought three1.2 GHz在我们的瑞士工厂多次将磁铁投放，这表明我们的设计具有稳健性。在整个开发阶段，我深表感谢他们的信任，我们从实现重要研究方面充满了满足感functionalstructural biology and IDPs.”
布鲁克的独特之处GHz级NMR magnets utilize a novel hybrid design with advanced high-temperature superconductor (HTS) in the inner sections and low-temperature superconductor (LTS) in the outer sections of the magnet. TheAscend™1.2 GHz是一种稳定的标准孔（54毫米）磁铁，具有类似于Bruker现有的1.0 GHz和1.1 GHz磁铁的高分辨率NMR的均匀性。1.2 GHz光谱仪可提供不同的超高场探针，包括用于溶液状态NMR和快速旋转MAS固态NMR探针的冷冻探针。在2020年的ENC，我们的科学合作者将介绍使用新的1.2 GHz 3毫米三个距离TCI获得的出色1.2 GHz高分辨率NMR数据冷冻探针®.
About Bruker Corporation(Nasdaq: BRKR)
Bruker is enabling scientists to make breakthrough discoveries and develop new applications that improve the quality of human life. Bruker’s high-performance scientific instruments and high-value analytical and diagnostic solutions enable scientists to explore life and materials at molecular, cellular and microscopic levels. In close cooperation with our customers, Bruker is enabling innovation, improved productivity and customer success in life science molecular research, in applied and pharma applications, in microscopy and nanoanalysis, and in industrial applications, as well as in cell biology, preclinical imaging, clinical phenomics and proteomics research and clinical microbiology. For more information, please visit:www.energie2point0.com.
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