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力量引领极限分辨率(XR的新时代™) in Mass Spectrometry

September 16, 2012

Breakthrough solariX XR™ System with Mass Resolution 10 Million Enables Novel Scientific Investigations

KYOTO, Japan--(BUSINESS WIRE)--Sep. 16, 2012-- At the 19thInternational Mass Spectrometry Conference (http://www.imsc2012.jp), Bruker today introduced the breakthrough newsolariX XRFourier Transform Mass Spectrometer (FTMS) with the revolutionaryParaCell™for extreme mass resolution greater than 10 million. This level of eXtreme Resolution (XR™) represents an order of magnitude quantum jump in mass resolving power, and opens up entirely new scientific frontiers in chemistry and molecular biology. ThesolariX XRwill initially be available to selected mass spectrometry research collaborators in a limited early access program.

The successfulsolariX™FTMS product line that was released in 2009 and quickly gained global acceptance as the premier solution for robust, ultra high-end mass spectrometry.

Frank Laukien, Ph.D, President and CEO of Bruker Corporation, stated: "The next-generationsolariX XRoffers a quantum leap in performance enabled by innovation in several cutting-edge technologies. As a result of these advances, thesolariX XRwill allow chemistry and molecular biology researchers for the first time to address some of the most complex and challenging samples with the ability to acquire mass spectra with an astounding10 million resolving power, setting a revolutionary new benchmark never before achieved in the history of mass spectrometry, and far exceeding that of all other mass spectrometry technologies."

The core technology in thesolariX XRis the academically acclaimed dynamically harmonizedParaCell™, developed by Professor Eugene Nikolaev and coworkers at the Russian Academy of Sciences in Moscow. This remarkably innovative design stabilizes the ion cyclotron resonance signal over a broad mass range for eXtreme Resolution scans of several minutes, thus enabling novel broadband, eXtreme Resolution scientific research, when high-throughput is not required. The effort necessary to achieve such extreme performance is now dramatically reduced by the operational simplicity of the new commercialParaCell, continuing the ease-of-use tradition set by thesolariXplatform.

In addition to the eXtreme Resolution performance enabled by theParaCelltechnology, the newsolariX XRalso provides record breaking performance at faster acquisition rates. ThesolariX XRis capable of providing resolving powers greater than 250,000 at m/z 400 in one second at 7T through optimization of processing algorithms used in the control software, including the use of broadband ICR absorption mode analysis. This enables high resolution workflows that provide greater information content with only half the time originally required, thus providing greater flexibility in experimental design.

Interdependent technologies:这些创新特性enabl的结合es thesolariX XRto reveal the fine structure in isotopic patterns that are uniquely specific to the exact molecular formulae of the detected compounds. For the first time ever, this will enable researchers in a variety of fields including metabolomics, environmental, petroleum and energy research, and proteomics to gain unique insights into highly complex samples in a way never before possible. The corresponding newSmartFormula XR™analysis software has been developed to interpret these distinctive fine structure isotope patterns in order to provide exact molecular formulae forZero-Defect™mass spectrometry.

Dr. Eugene Nikolaev, inventor of theParaCellgeometry, stated: "The advantages of dynamic harmonization enable researchers to attain performance that was never before achievable, and as a result pursue advanced scientific research that will prove more efficient than current mass spectrometry strategies. The invention is based on the newly discovered principle of effective electric field formation by averaging of the static field via cyclotron motion, and a deep understanding of mass resolution limitations through supercomputer simulations of ion cloud motions in different types of FT-ICR cells."

The initial release of the exciting newsolariX XRsystem will be strategically focused on advanced mass spectrometry research laboratories developing new principles and novel workflows for chemical and biomolecular analysis based on innovative eXtreme Resolution technology. These key collaborators will create novel analytical approaches based on atomic level data never before available in mass spectrometry, which are expected to have a profound effect on a wide variety of molecular scientific disciplines.

ThesolariX XRis a fully integrated novel system with multiple new component technologies. It is available with a dedicated 7 tesla magnet, and previous generationsolariXsystems are not upgradeable toXRtechnology. For more information on thesolariX, please visit//www.energie2point0.com/solariX

About Bruker Corporation

Bruker Corporation (NASDAQ: BRKR) is a leading provider of high-performance scientific instruments and solutions for molecular and materials research, as well as for industrial and applied analysis. For more information, please visit//www.energie2point0.com.

Photos/Multimedia Gallery Available:http://www.businesswire.com/cgi-bin/mmg.cgi?eid=50407878&lang=en

Source: Bruker Corporation

Bruker
Michael L. Easterling, Ph.D., +1-978-663-3660, x1488
FTMS Commercial Product Manager
mle@bdal.com

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