VANCOUVER, British Columbia--(BUSINESS WIRE)--May. 21, 2012-- At ASMS 2012, Bruker announced the introduction of its newnano-AdvanceUHPLC system for capillary and nano-flow LC-MS applications. Combining the novelnano-AdvanceUHPLC with Bruker's leading mass spectrometry platforms, including theamaZonIon Trap series andmaxisUHR-TOF series, further enhances Bruker's integrated solutions for proteomics.
The newnano-AdvanceUHPLC delivers reproducible retention times with accurate gradients down to 50nL/min. With run-to-run sample carryover typically less than 0.005%, thenano-AdvanceUHPLC delivers industry-leading separation performance critical to the success of many proteomics workflows. Thenano-AdvanceUHPLC was specifically designed to eliminate dead volume and gradient delay wherever possible. When combined with Bruker's uniqueCaptiveSpray Ionsource, the combination can deliver up to twice the MS utilization rate of typical nano-LC systems coupled to nanospray MS sources. The increased mass spectrometry utilization rate enables more proteins and peptides to be identified and quantified in a single LC-MS run. This is especially significant for detection of low abundance proteins in complex samples, which are easily missed due to the inability of the mass spectrometer to keep up with significant numbers of co-eluting peptides.
Thenano-AdvanceUHPLC delivers precise nanoliter-scale flow rates without the need for any split-flow due to the incorporation of two high performance direct drive syringe pumps. There is also a third pump for trap loading and 2D-LC applications. In conjunction with theCaptiveSpray Ionsource, thenano-Advanceloading capacity is significantly higher than for conventional nano-LC systems, resulting in higher dynamic range and increased protein coverage and identification.
Dr. Kerry Nugent, Bruker's Senior Vice President - Liquid Chromatography, commented: "With the introduction of thenano-AdvanceUHPLC, Bruker has taken another step to expand our position as a leading provider of mass spectrometry-based proteomics solutions. The ability of thenano-AdvanceUHPLC, in conjunction with theCaptiveSpray Ionsource, to deliver increased MS productivity, enables the identification of more proteins with greater confidence in the same period of time."
About Bruker Corporation
Bruker Corporation (NASDAQ: BRKR) is a leading provider of high-performance scientific instruments and solutions for molecular and materials research, as well as for industrial and applied analysis. For more information, please visit//www.energie2point0.com.
Source: Bruker Corporation
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