ESI-ITMS

amaZon speed

The amaZon speed ion trap series sets new analytical standards for proteomics and small molecule applications

Leading ion trap design

Ultimate MS/MS efficiency

amaZon-speed-web

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ESI-ITMS

amaZon speed

Sensitivity
Leading dual ion funnel technology provides 10x higher MS/MS sensitivity.
Efficiency
大大增加MS / MS占空比,以获得更多的生产性数据采集.
速度
Fundamental improvements to the well proven amaZon platform offer dramatically enhanced speed.
Protein ID
Sets new standards in protein identification due to its enhanced MS/MS speed, new faster isolation and SMART fragmentation.

características.

amaZon speed

通过创新无与伦比的离子陷阱性能

The amaZon speed offers:

  • 大大增加MS / MS占空比,以获得更多的生产性数据采集
  • High ion trap mass accuracy through proprietary RF generator design
  • Leading dual ion funnel technology for unparalleled sensitivity
  • 零延迟交替用于极性切换,至少为20 Hz MS采集速度
  • New SMART isolation and fragmentation
  • Unrivaled scan speed of 52,000 u/sec at a peak width < 0.5 u for resolution of doubly charged ions
  • Support of fastest UPLC applications at a maximum duty cycle

双离子funnel
Delivering unmatched sensitivity by dual ion funnel inlet.

Fast scanning mass analyzer
Provides several standard scan ranges up to 52,000 u/sec

Beneficios

amaZon speed

Turning speed into solutions

亚马逊速度离子陷阱为小分子和筛选应用设定了分析标准。良好的亚马逊平台的基本改进显着提高了速度,质量分辨率,MS / MS效率和可再现的定量,提供了无与伦比的性能。

With a 10x higher MS/MS sensitivity over current platforms and Zero Delay Alternating switching at a minimum of 20 Hz MS acquisition rate, this ion trap system delivers increased performance to meet growing demand from the pharmaceutical, chemical and clinical markets.

Aplicaciones

重新定位离子捕集性能为小分子应用

The amaZon speed builds upon Bruker’s vast experience in ion trap technology and is designed specifically to enhance capabilities in research areas such as proteomics, metabolomics, forensic compound screening and identification, and detailed chemical analysis.

MS for Structure Analysis
鉴定药物代谢物并验证其结构在制药发现和发展中起着至关重要的作用。像FragmentExplorer这样的软件功能是结构确认的理想工具,利用亚马逊速度离子陷阱的快速和敏感的逐步逐步剖析。Bruker的Metaboliteolss软件套件提供自信的代谢物预测,以及新化合物的检测和解释。

散步罗盘Openaccessaccess工作流程
The intuitive and workflow-oriented GUI of the Compass OpenAccess software supports the flexibility and speed of the amaZon speed as an ideal solution for multi-user industrial, clinical or teaching labs. The web-based client server system is ideally suited for workflows such as quality control (QC), recombinant protein MW verification or automatic library searches.

Drug quantitation
Reliable and routine quantification is a task so far reserved for triple quadrupole instruments. The enhanced speed and reproducibility of the amaZon speed in MRM experiments enables the reliable quantification of target compounds in diverse matrices.

Translating speed into proteomic information

Bottom-up analysis
蛋白质组的复杂性仍然挑战分析技术。由于发生后改变的高动态范围和复杂性需要最大的速度和敏感性来捕获尽可能多的肽。

The enhanced MS/MS speed, faster isolation and SMART fragmentation capabilities of the amaZon speed ion trap set new standards in protein identification. This results in the identification of > 1200 unambiguously identified proteins in a single LC-MS/MS run from 1 µg E. coli digest.

Excellent dynamic range
The UPS-2 standard is a mixture of 48 proteins spanning a concentration range of 6 decades in total. The amaZon speed allows protein identifications over 5 concentration levels in a single run.

生产力,鲁棒性和高序列覆盖率
The amaZon speed is equipped with the high-transmission, robust CaptiveSpray source for high performance and reproducibility in bottom-up studies.

Survey view of an E.coli digest (1 µg) separated by a nano UHPLC using a 25 cm column and a 3 h LC gradient. MS detection was performed using the amaZon speed ETD system equipped with a CaptiveSpray ion source.

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